Examine Clinical Evidence in Commonly †Free Samples to Students

Question: Discuss about the Examine Clinical Evidence in Commonly. Answer: Introduction The paper deals with the PICO question generated in response to the case study of Peggy, a 65 year old lady suffering from degenerative osteoarthritis in her Knees. In response to the PICO question the paper performs database search to retrieve relevant articles. The findings from the two best research results will be summarised in the paper. The clinical question is designed to compare the effectiveness of taking fish oil degenerative osteoarthritis in older women (Peggy) to those not taking or relying on alternate remedy such as medication. The question is designed with the aim to obtain clinical evidence on improvement of arthritis on taking fish oil. Based on the real evidence obtained the patient can be advocated or recommended to take fish oil. The rationale for the study is the million of Australians consuming fish oil as remedy for arthritis (Pittaway et al., 2015). Two databases have been used to search for the evidence based on the question. It includes PubMed and Cochrane Management. PubMed is the reliable database for more than 27 million articles. This free search engine allows to access other databases management such as MEDLINE to conduct research on nursing, dental, medical, health care and selected life science journals. The other advantages include automatic term mapping that marked the search more comprehensive when compared to other versions. It gives quick access to new articles published and allows for efficient information retrieval by the end users (Patten, 2017). The other database CINAHL is the definitive research tool. It is the most comprehensive database for the nursing, medical and allied health care. For nurses around the globe it is the most respected research tool (Besner, 2015). Key words terms/phrases Alternative words P Osteoarthritis women, osteoarthritis older adults, Osteoarthritis patients OR knee osteoarthritis, osteoarthritis pain OR knee pain women I Fish oil osteoarthritis, fish oil pain relief, osteoarthritis fish oil Osteoarthritis patients OR fish oil, Fish oil OR osteoarthritis C High dose fish oil, low dose fish oil, Dietary fatty acids, omega 3 fish oil, efficacy fish oil Low dose fish oil OR Dietary fish oil Fish oil OR marine oil O Fish oil knee treatment, Fish oil arthritis pain relief, Efficacy fish oil Omega-3 fatty acid osteoarthritis relief OR fish oil arthritis relief Efficacy fish oil Or Pain relief For CINAHL Action Search mode Results Limiters/Expanders S1 SmartText searching- Efficacy of fish oil in osteoarthritis treatment 217 Expander: Apply related words S2 SmartText searching- Fish oil in arthritis treatment 167 Expander: Apply related words S3 Find all my search terms- Osteoarthritis patients OR Fish oil 140 Publication type- The journal of clinical nutrition S4 Find any of my search term - fish oil in arthritis pain 55 Full text, 2013-2017, Peer reviewed article Publication type- The journal of clinical nutrition S5 Boolean/Phrase- Osteoarthritis patients AND fish oil, 46 Full text, 2013-2017, Peer reviewed article Publication type- The journal of nutrition, health aging S6 Boolean Phrase- Fish oil AND osteoarthritis treatment 5 Full text, 2013-2017, Peer reviewed article (Source: Richardson-Tench et al., 2016) Relevant results Two of the research articles were most relevant to the PICO question and appeared to address the question. Hill et al. (2016) conducted a randomised, double bind trial to determine if the high dose fish oil is effective in treating osteoarthritis. The researcher enrolled 202 patients with both regular knee pain and those with osteoarthritis. The researchers compared the efficacy of the high dose fish oil consumption with the low dose. All the participants recruited were above 40 years with the knee pain score above 20 mm on a 0100?mm scale. During the run in period the patients who can tolerate the fish oil were allocated to two treatment arms that is high dose and low dose. The process involved the computer generated random allocation. Both the groups showed improvement. When compared with the high dose group, the low dose group had greater improvement in the pain and function scores when administered for 2 years. Further there was no difference in the loss of cartilage volume, BML core, and quality of life. At the differences of one year there was no significant difference between both the groups. The benefit of using fish oil is noted prominently in the participants however, there is no remarkable improvement found with the increase in dosage. Overall better efficacy of fish oil in reducing pain was found in two years of time. Senftleber et al. (2016), conducted systematic review and met analysis of the randomised trials to determining the effectiveness of taking fish oil. Six databases were searched and 30 trials were found to meet the inclusion criteria. There was a substantial heterogeneity present. Overall the pooled standard mean differences revealed a favourable effect. The meta analysis results showed a significant effect of fish oil on the rheumatoid arthritis patients but not on the osteoarthritis (5 trials; SMD, -0.17, 95% CI, -0.57 to 0.24). It can be concluded that the results showed a moderate quality evidence of the use of fish oil to alleviate pain in patients with arthritis. Conclusion Since strong evidence from quantitative paper and moderate level evidence from the qualitative paper is found Mrs Peggy can be advocated to take fish oil in addition to normal treatment. In conclusion there is a need of intense research to determine the effectiveness of fish oil in osteoarthritis. References Besner, G. E. (2015). This goal of this review was to examine the clinical evidence in support of commonly utilized measures intended to reduce complications following elective colorectal surgery. Literature searches were performed to identify relevant studies from Medline, PubMed, and Cochrane databases management. The American Pediatric Surgery Association Outcomes and Clinical Trials Committee selected eight questions to address...Journal of Pediatric Surgery,50(1), 192-200. Besner, G. E. (2015). This goal of this review was to examine the clinical evidence in support of commonly utilized measures intended to reduce complications following elective colorectal surgery. Literature searches were performed to identify relevant studies from Medline, PubMed, and Cochrane databases. The American Pediatric Surgery Association Outcomes and Clinical Trials Committee selected eight questions to address...Journal of Pediatric Surgery,50(1), 192-200. Hill, C. L., March, L. M., Aitken, D., Lester, S. E., Battersby, R., Hynes, K., ... Jones, G. (2016). Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose.Annals of the rheumatic diseases,75(1), 23-29. Patten, M. L. (2017).Understanding research methods: An overview of the essentials. Taylor Francis. Pittaway, J. K., Chuang, L. T., Ahuja, K. D. K., Beckett, J. M., Glew, R. H., Ball, M. J. (2015). Omega-3 dietary Fatty Acid status of healthy older adults in Tasmania, Australia: an observational study.The journal of nutrition, health aging,19(5), 505-510. Richardon-Tench, M., Brown, S. (2014). Meeting the needs of cognitively impaired older adults in day surgery: a review of literature.Day Surgery Australia,13(2), 18. Senftleber, N. K., Nielsen, S. M., Andersen, J. R., Bliddal, H., Tarp, S., Lauritzen, L., ... Christense, R. (2016). PT09. 4: Fish Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials.Clinical Nutrition,35, S40.